产品货号:
Z24823
中文名称:
PSMD4抗体
英文名称:
Anti-PSMD4 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PSMD4 Antibody |
指标别名 | PSMD4;MCB1;26S proteasome non-ATPase regulatory subunit 4;26S proteasome regulatory subunit RPN10;26S proteasome regulatory subunit S5A;Antisecretory factor 1;AF;ASF;Multiubiquitin chain-binding protein |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF,IF,FCM,Direct ELISA |
基因名称 | PSMD4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human PSMD4 recombinant protein (Position:M1-E322). |
计算分子量 | 41KD |
实际分子量 | 55KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | 26S proteasome non-ATPase regulatory subunit 4,also as known as 26S Proteasome Regulatory Subunit Rpn10 (systematic nomenclature),is an enzyme that in humans is encoded by the PSMD4 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes,a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits;2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base,which contains 6 ATPase subunits and 2 non-ATPase subunits,and a lid,which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome,the immunoproteasome,is the processing of class I MHC peptides.This gene encodes one of the non-ATPase subunits of the 19S regulator lid.Pseudogenes have been identified on chromosomes 10 and 21. |
Uniprot ID | P55036 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
基因名全称 | proteasome 26S subunit ubiquitin receptor,non-ATPase 4 |
蛋白名全称 | 26S proteasome non-ATPase regulatory subunit 4 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunofluorescence (IF) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells Direct ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
Gene ID | 5710 |
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